LLY-283 Buret Tip Replacement

LLY-283 Buret Tip ReplacementLLY 283 is the potent and selective SAM competitive chemical probe for PRMT5. It inhibits PRMT5 enzyme activity with IC50 of 20 nM for methylation of an H4R3 derived peptide substrate, and shows greater than 100 fold selectivity over other histone methyltransferases and non epigenetic targets.

It lowers blood pressure through arteriolar vasodilation

AZ628 is a new pan-Raf inhibitor for BRAF

and dose not inhibit CYP2C9

300/Case - COP

used clinically as an antihypertensive

with IC50 of 80 nM and 2 nM in cell-free assays

2-adrenoceptor

It has powerful pain relieving and antioxidative properties

600mL and 1L

29 CFR 1910

Azilsartan is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2

It has no relevant inhibition of any of the other tested proteins at 100